Manganese catalysed enantioselective hydrogenation of in situ-synthesised imines: efficient asymmetric synthesis of amino-indane derivatives
Manganese catalysed enantioselective hydrogenation of in situ-synthesised imines: efficient asymmetric synthesis of amino-indane derivatives
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DOI：
10.1039/d3gc00399j
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发表时间：
2023-05-03
期刊：
影响因子：
9.8
通讯作者：
Clarke, Matthew L.
中科院分区：
文献类型：
--
作者：
Oates, Conor L.;Goodfellow, Alister S.;Clarke, Matthew L.
一种表面配位的P，N，N配体的锰催化剂以高的对映选择性催化由茚满酮衍生物衍生的亚胺的氢化。不需要活化基团，可以原位生成亚胺。选择性可以通过DFT计算合理化。
A manganese catalyst of a facially coordinating P,N,N ligand catalyses the hydrogenation of imines derived from indanone derivatives with high enantioselectivity. There is no requirement for an activating group and imines can be generated in situ. The selectivity can be rationalised by DFT calculations.