KDOQI US commentary on the 2012 KDIGO clinical practice guideline for management of blood pressure in CKD.

KDOQI US commentary on the 2012 KDIGO clinical practice guideline for management of blood pressure in CKD.
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DOI:
10.1053/j.ajkd.2013.03.018
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发表时间:
2013-08
期刊:
American journal of kidney diseases : the official journal of the National Kidney Foundation
影响因子:
--
通讯作者:
Townsend RR
Townsend RR
中科院分区:
其他
文献类型:
--
作者:
Taler SJ;Agarwal R;Bakris GL;Flynn JT;Nilsson PM;Rahman M;Sanders PW;Textor SC;Weir MR;Townsend RR

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为响应2012年KDIGO(肾脏疾病:改善全球结局)关于非透析慢性肾脏疾病患者血压管理的指南,美国国家肾脏基金会组织了一组美国高血压和移植肾脏学专家,以审查这些建议,并在当前美国临床实践和关注的背景下对其相关性进行评论。最重要的信息是缺乏临床试验证据来提供强有力的循证建议。对于蛋白尿正常至轻度增加的CKD患者,糖尿病和非糖尿病患者的目标血压均放宽至≤140/90 mm Hg。相比之下,KDIGO继续建议中度或重度白蛋白尿增加的慢性肾脏疾病患者和所有肾移植受者的目标血压≤130/80 mm Hg,无论是否存在蛋白尿,没有支持数据。专家组认为KDIGO的建议总体上是合理的,但缺乏足够的证据支持,非常需要进行更多的研究。
In response to the 2012 KDIGO (Kidney Disease: Improving Global Outcomes) guideline for blood pressure management in patients with chronic kidney disease not on dialysis, the National Kidney Foundation organized a group of US experts in hypertension and transplant nephrology to review the recommendations and comment on their relevancy in the context of current US clinical practice and concerns. The overriding message was the dearth of clinical trial evidence to provide strong evidence-based recommendations. For patients with CKD with normal to mildly increased albuminuria, goal blood pressure has been relaxed to ≤140/90 mm Hg for both diabetic and nondiabetic patients. In contrast, KDIGO continues to recommend goal blood pressure ≤130/80 mm Hg for patients with chronic kidney disease with moderately or severely increased albuminuria and for all renal transplant recipients regardless of the presence of proteinuria, without supporting data. The expert panel thought the KDIGO recommendations were generally reasonable but lacking in sufficient evidence support and that additional studies are greatly needed.
糖尿病的医疗标准 - 2010年。
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