Neurophysiological mechanisms in acceptance and commitment therapy in opioid-addicted patients with chronic pain.
Neurophysiological mechanisms in acceptance and commitment therapy in opioid-addicted patients with chronic pain.
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DOI：
10.1016/j.pscychresns.2016.03.001
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发表时间：
2016-04-30
期刊：
影响因子：
--
通讯作者：
Robin DA
中科院分区：
文献类型：
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作者：
Smallwood RF;Potter JS;Robin DA
接受与承诺疗法（ACT）已被有效地用于治疗慢性疼痛和物质使用障碍。鉴于这些结果和治疗这两种疾病的合并症的迫切需要，在患有慢性疼痛和阿片类药物成瘾的个体中实施了试点ACT治疗。这项初步研究支持使用神经生理学来表征治疗效果，并揭示，在ACT治疗后，患有这种合并症的参与者由于疼痛刺激和休息时的连通性而表现出大脑激活减少。
Acceptance and Commitment Therapy (ACT) has been effectively utilized to treat both chronic pain and substance use disorder independently. Given these results and the vital need to treat the comorbidity of the two disorders, a pilot ACT treatment was implemented in individuals with comorbid chronic pain and opioid addiction. This pilot study supported using neurophysiology to characterize treatment effects and revealed that, following ACT, participants with this comorbidity exhibited reductions in brain activation due to painful stimulus and in connectivity at rest.