The DAS28 in rheumatoid arthritis and fibromyalgia patients

The DAS28 in rheumatoid arthritis and fibromyalgia patients
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DOI:
10.1093/rheumatology/keh322
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发表时间:
2004-12-01
期刊:
影响因子:
5.5
通讯作者:
Rintelen, B
Rintelen, B
中科院分区:
医学1区
文献类型:
--
作者:
Leeb, BF;Andel, I;Rintelen, B

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Objective.比较类风湿性关节炎(RA)和纤维肌痛(FM)患者的DAS 28(疾病活动性评分,包括28个关节计数)值,并确定高疼痛水平和受损情绪是否影响DAS 28值。DAS 28值计算在62例连续RA患者和26例患有FM的患者。使用Student t检验比较DAS 28评分值以及患者队列的单项。采用因子分析和Cronbach’s alpha检验评价量表的项目权重和内部一致性。RA患者的平均DAS 28评分为4.23(+/-1.2;范围0.77-7.46),FM患者的平均DAS 28评分为4.04(+/-1.13;范围1.19-6.28)。RA和FM患者的DAS 28值在统计学上无显著差异。然而,比较得分的单个组成部分,高度显著性差异(P
Objective. To compare the DAS28 (Disease Activity Score including a 28-joint count) values of rheumatoid arthritis (RA) and fibromyalgia (FM) patients, and to establish whether high pain levels and impaired mood influence DAS28 values.Methods. DAS28 values were calculated in 62 consecutive patients with RA and in 26 patients suffering from FM. Values for DAS28 scores as well as for the single items of the patient cohorts were compared using Student's t-tests. To evaluate the item weighting and internal consistency of the total score factor analysis was performed and Cronbach's alpha calculated.Results. RA patients showed a mean DAS28 score of 4.23 (+/-1.2; range 0.77-7.46) and in FM patients the mean DAS28 came to 4.04 (+/-1.13; range 1.19-6.28). DAS28 values of RA and FM patients were not significantly different statistically. Comparing the single components of the score, however, highly significant differences (P