REACTIVE LYMPHOID HYPERPLASIA OF THE STOMACH
REACTIVE LYMPHOID HYPERPLASIA OF THE STOMACH
复制标题
胃反应性淋巴增生
DOI：
--
复制
发表时间：
1980
期刊：
影响因子：
--
通讯作者：
T. Shimamine
中科院分区：
文献类型：
--
作者：
S. Mori;N. Mohri;T. Shimamine
对手术切除的胃进行了组织病理学检查，18例病例被归类为反应性淋巴样增生（RLH）。本文观察了10例胃恶性淋巴瘤（ML）和10例正常胃组织中浸润性免疫球蛋白（IG）细胞的分布和类型。发现11例RLH和1例ML的病变中，许多携带不同类型IG的淋巴细胞以混合的方式存在（多特异性组）。同时，3例RLH病例和2例ML病例中的淋巴细胞仅携带单一特异性IG（单特异性组）。在其他情况下，携带IG的细胞数量不足以得出任何明确的结论（未确定组）。据推测，无论组织病理学诊断如何，单特异性组可能属于B细胞型肿瘤类别，多特异性组可能属于真正反应性过程类别。重新检查了区分胃反应性过程和淋巴样肿瘤的可能组织病理学标准，并强调了对这些病例进行免疫组化研究的重要性。
The surgically excised stomachs were re‐examined histopathologically, and eighteen cases were placed in the category of reactive lymphoid hyperplasia (RLH). The distribution and the classes of infiltrating immunoglobulin (Ig) bearing cells were examined on lesions of RLH cases together with ten histopathologically determined malignant lymphomas (ML) of the stomach and the control stomachs. It was found that in eleven cases of RLH and one case of ML, many lymphoid cells bearing different classes of Ig were present in those lesions in an intermingled way (polyspecific group). Meanwhile, lymphoid cells in three RLH cases and two ML cases bore only a single mono‐specific Ig (monospecific group). In other cases, the number of Ig bearing cells were not sufficient to reach any clear conclusions (undetermined group). It was speculated that regardless of the histopathological diagnosis, the mono‐specific group might belong to the category of neoplasm of B cell type and the polyspecific group in the category of true reactive process. The possible histopathological criteria for differentiation of the reactive process and lymphoid neoplasm of the stomach were re‐checked, and the importance of immunohistochemical study on these cases were stressed.