Echoplanar BOLD fMRI of brain activation induced by concurrent transcranial magnetic stimulation
Echoplanar BOLD fMRI of brain activation induced by concurrent transcranial magnetic stimulation
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DOI：
10.1097/00004424-199806000-00004
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发表时间：
1998-06-01
影响因子：
6.7
通讯作者：
George, MS
中科院分区：
文献类型：
--
作者：
Bohning, DE;Shastri, A;George, MS
原理和说明。作者证明了在MR扫描仪内结合经颅磁刺激（TMS）和功能磁共振成像（fMRI）以非侵入性刺激和成像局部脑活动的可行性。三名志愿者在标准1.5 T MR扫描仪内进行了基于回波平面血氧水平依赖（BOLD）的TMS反应的fMRI研究，使用独立的计算机控制交错回波平面图像采集和非铁磁TMS线圈刺激右拇指初级运动皮层。显著（P
RATIONALE AND OBJECTIVES. The authors demonstrate the feasibility of combining transcranial magnetic stimulation (TMS) and functional magnetic resonance imaging (fMRI) inside an MR scanner to noninvasively stimulate and image regional brain activity.METHODS. Echoplanar blood oxygen level dependent (BOLD)-based fMRI studies of TMS response were performed on three human volunteers inside a standard 1.5 T MR scanner using independent computer control to interleave echoplanar image acquisition and stimulation of right thumb primary motor cortex with a nonferromagnetic TMS coil.RESULTS. Significant (P