A sexual dimorphism in hypothalamic arginine vasotocin (AVT) gene expression and AVT plasma levels in the Japanese quail (Coturnix coturnix japonica) in response to water deprivation
A sexual dimorphism in hypothalamic arginine vasotocin (AVT) gene expression and AVT plasma levels in the Japanese quail (Coturnix coturnix japonica) in response to water deprivation
复制标题
DOI：
10.1006/gcen.1999.7400
复制
发表时间：
2000-01-01
影响因子：
2.7
通讯作者：
Cornett, LE
中科院分区：
文献类型：
--
作者：
Chaturvedi, CM;Chowdhary, A;Cornett, LE
为了研究鸟类精氨酸催产素（AVT）释放的渗透压控制中可能存在的性二态性，对年龄匹配的雄性和雌性日本鹌鹑进行了水剥夺。观察到的血浆渗透压升高伴随着血浆AVT水平升高。血浆中催产素水平没有改变与水剥夺。通过血浆AVT水平与血浆渗透压之间关系的斜率确定的AVT释放的渗透控制灵敏度，男性显著高于女性（P < 0.05）。通过北方印迹分析，与正常含水的鸟类相比，缺水的雄性和雌性日本鹌鹑的下丘脑AVT基因转录水平分别增加了2.3 +/- 0.14和3.5 +/- 0.13倍。我们的数据表明日本鹌鹑AVT释放的渗透压控制和下丘脑AVT基因表达存在性别相关差异。(C)北京大学出版社.
To examine a possible sexual dimorphism in the osmotic control of arginine vasotocin (AVT) release in birds, age-matched male and female Japanese quail were subjected to water deprivation. The observed increased plasma osmolalities were accompanied by increased plasma AVT levels. Plasma mesotocin levels did not change with water deprivation. The sensitivity of the osmotic control of AVT release as determined by the slope of the relationship between plasma AVT levels and plasma osmolalities was significantly (P < 0.05) higher in males than in females. By Northern blot analysis, levels of hypothalamic AVT gene transcripts were increased 2.3 +/- 0.14- and 3.5 +/- 0.13-fold in water-deprived male and female Japanese quail, respectively, compared to normally hydrated birds. Our data suggest gender-related differences in the osmotic control of AVT release and in hypothalamic AVT gene expression in the Japanese quail. (C) 2000 Academic Press.