Quintuple-modality (SERS-MRI-CT-TPL-PTT) plasmonic nanoprobe for theranostics

Quintuple-modality (SERS-MRI-CT-TPL-PTT) plasmonic nanoprobe for theranostics
复制标题

用于治疗诊断的五模态 (SERS-MRI-CT-TPL-PTT) 等离子体纳米探针

DOI:
10.1039/c3nr03762b
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发表时间:
2013-01-01
期刊:
影响因子:
6.7
通讯作者:
Vo-Dinh, Tuan
Vo-Dinh, Tuan
中科院分区:
材料科学2区
文献类型:
--
作者:
Liu, Yang;Chang, Zheng;Vo-Dinh, Tuan

文献摘要

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相似文献

利用金纳米星开发了一种独特的五模态治疗诊断纳米探针(QMT),用于表面增强拉曼散射(Sers)、磁共振成像(MRI)、计算机断层扫描(CT)、双光子发光(TPL)成像和光热治疗(PTT)。合成的金纳米星用Sers报告分子标记,并与MRI造影剂Gd 3+连接。体外实验表明,开发的QMT纳米探针是一种潜在的治疗诊断剂,用于未来的生物医学应用。
A unique quintuple-modality theranostic nanoprobe (QMT) is developed with gold nanostars for surface-enhanced Raman scattering (SERS), magnetic resonance imaging (MRI), computed tomography (CT), two-photon luminescence (TPL) imaging and photothermal therapy (PTT). The synthesized gold nanostars were tagged with a SERS reporter and linked with an MRI contrast agent Gd3+. In vitro experiments demonstrated the developed QMT nanoprobe to be a potential theranostic agent for future biomedical applications.