Stereoselective synthesis of polyfunctionalised hydroxylated cyclopentanes from dihydroxylated 2-cyclopentenone derivatives
Stereoselective synthesis of polyfunctionalised hydroxylated cyclopentanes from dihydroxylated 2-cyclopentenone derivatives
复制标题
DOI：
10.1016/s0040-4020(01)00590-7
复制
发表时间：
2001-07-16
期刊：
影响因子：
2.1
通讯作者：
Vile, S
中科院分区：
文献类型：
--
作者：
Caddick, S;Cheung, S;Vile, S
二羟基化的环戊烯酮可以通过碱介导的异构化反应容易地合成。这些物质和它们的衍生物可用于通过参与各种立体选择性转化来提供广泛的合成有用的中间体。其中包括：亲核和共轭加成、分子间环加成、分子内自由基环化和钯介导的偶联反应。(C)2001 Elsevier Science Ltd. Au版权所有。
Dihydroxylated cyclopentenones can be readily synthesised via a base mediated isomerisation reaction. These species and their derivatives can be used to provide a wide range of synthetically useful intermediates by participation in a variety of stereoselective transformations. These include: nucleophilic and conjugate addition, intermolecular cycloaddition, intramolecular free-radical cyclisation and palladium mediated coupling reactions. (C) 2001 Elsevier Science Ltd. AU rights reserved.