Sinister symbiosis: pathological hematopoietic-stromal interactions in CML.
Sinister symbiosis: pathological hematopoietic-stromal interactions in CML.
复制标题
险恶的共生:CML 中的病理性造血基质相互作用。
DOI:
10.1016/j.stem.2013.08.009
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发表时间:
2013
期刊:
影响因子:
23.9
通讯作者:
Ebert,BenjaminL
中科院分区:
文献类型:
--
作者:
Mullally,Ann;Ebert,BenjaminL
The impact of myeloid malignancies on the nonhematopoietic components of the bone marrow remains poorly understood. In this issue ofCell Stem Cell, Schepers et al. (2013) describe how malignant myeloid cells alter the endosteal hematopoietic stem cell (HSC) niche, resulting in the expansion of osteoblastic lineage cells that preferentially support malignant HSCs.