Supplementing Fat Grafts with Adipose Stromal Cells for Cosmetic Facial Contouring
Supplementing Fat Grafts with Adipose Stromal Cells for Cosmetic Facial Contouring
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用脂肪基质细胞补充脂肪移植物以实现美容面部轮廓
DOI：
10.1111/dsu.12058
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发表时间：
2013-03-01
影响因子：
2.4
通讯作者：
Lu, Feng
中科院分区：
文献类型：
--
作者：
Li, Jie;Gao, Jianhua;Lu, Feng
许多方法已被提出来提高脂肪移植物的存活率，但没有明确的治疗方法。间质血管成分（SVF）辅助细胞疗法为提高脂肪移植物存活率提供了新的前景。目的探讨自体脂肪移植术后补充SVF是否能改善移植物的固位。方法回顾性分析2010年10月至2012年1月38例接受SVF联合脂肪移植（n=26）和单纯脂肪移植（n=12）的女性患者的临床资料。每例患者均在术前和术后6个月接受计算机断层扫描并拍摄照片。Philips Extended Brilliance Workspace用于分析体积增大。结果所有患者术后外观均有不同程度的改善。随访期间未发现并发症。SVF的脂肪存活率（64.8 +/- 10.2%）高于单纯脂肪移植（46.4 +/- 9.3%）（p
Background Numerous methods have been proposed to enhance the survival of fat grafts, but no definitive treatment is available. Stromal vascular fraction (SVF)-assisted cell therapy offers new perspectives for improving fat graft survival. Objectives To determine whether SVF supplementation could improve graft retention in patients undergoing autologous fat grafting for cosmetic improvement of facial contour. Methods We retrospectively analyzed data from 38 women who underwent fat transplantation with SVF (n=26) or fat grafting alone (n=12) between October 2010 and January 2012. Each patient underwent computed tomography, and photographs were taken before and 6months after surgery. The Philips Extended Brilliance Workspace was used for analysis of volume augmentation. Results All patients showed cosmetic improvements, but the degree varied. No complications were evidenced during follow-up. Fat survival was higher with SVF (64.8 +/- 10.2%) than fat grafting alone (46.4 +/- 9.3%) (p