Myelofibrosis and systemic lupus erythematosus: reversal of fibrosis with high-dose corticosteroid therapy.
Myelofibrosis and systemic lupus erythematosus: reversal of fibrosis with high-dose corticosteroid therapy.
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骨髓纤维化和系统性红斑狼疮：用大剂量皮质类固醇治疗逆转纤维化。
DOI：
10.1159/000204592
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发表时间：
1992
影响因子：
2.4
通讯作者：
T. Kaneko
中科院分区：
文献类型：
--
作者：
Yasushi Inoue;Atsushi Matsubara;Shigeru Okuya;Koichiro Okafuji;Kohei Kaku;T. Kaneko
报告1例系统性红斑狼疮合并骨髓纤维化。急性血小板减少症和出血倾向的发展，在一个24岁的女性SLE。由于骨髓纤维化，骨髓抽吸不成功。甲基强的松龙冲击治疗逆转血小板减少症和骨髓纤维化。文献回顾显示系统性红斑狼疮与骨髓纤维化并存是一种罕见的情况。据我们所知，只有7例病例有详细报道。本病例是第3例皮质类固醇逆转骨髓纤维化的病例。
A case of myelofibrosis in association with systemic lupus erythematosus (SLE) is reported. Acute thrombocytopenia and a bleeding tendency developed in a 24-year-old woman with SLE. Bone marrow aspiration was unsuccessful due to myelofibrosis. Pulse therapy with methylprednisolone reversed both thrombocytopenia and myelofibrosis. A review of the literature revealed that the coexistence of SLE and myelofibrosis is a rare occurrence. Only 7 cases, to our knowledge, have ever been reported in detail. The present case is the 3rd in which myelofibrosis was reversed by corticosteroids.