Impact of drug-eluting stents with different coating strategies on stent thrombosis: A meta-analysis of 19 randomized trials
Impact of drug-eluting stents with different coating strategies on stent thrombosis: A meta-analysis of 19 randomized trials
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DOI：
10.5603/cj.a2014.0002
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发表时间：
2014-01-01
影响因子：
2.9
通讯作者：
Yao, Yali
中科院分区：
文献类型：
--
作者：
Niu, Xiaowei;Yang, Cuiling;Yao, Yali
背景：与永久性聚合物DES （PP-DES）相比，生物可降解聚合物药物洗脱支架（BP-DES）是否能提高安全性，特别是在支架血栓形成（ST）方面，仍不确定。我们的目的是比较BP-DES与PP-DES治疗的患者的短期和长期结局和ST风险。方法：检索Medline、Embase、Web of science、CENTRAL数据库和会议记录/摘要，比较BP-DES和PP-DES的随机对照试验（rct）。主要终点是比较总体和不同时间类型的明确/可能st的风险。其他临床结果是靶病变血运重建术（TLR）、心肌梗死（MI）和短期内全因死亡(
Background: Whether drug-eluting stents with biodegradable polymers (BP-DES) improve safety, especially with respect to stent thrombosis (ST) compared with permanent polymers DES (PP-DES), remains uncertain. We aimed to compare the short-and long-term outcomes and the ST risk in patients treated with BP-DES vs. PP-DES.Methods: We searched Medline, Embase, Web of science, CENTRAL databases, and conference proceedings/abstracts for randomized controlled trials (RCTs) comparing BP-DES with PP-DES. The primary endpoint was to compare the risks of overall and different temporal categories of definite/probable ST. Other clinical outcomes were target lesion revascularization (TLR), myocardial infarction (MI), and all-cause death in short-term (