PLASMA-RENIN ACTIVITY, ANGIOTENSIN-II, AND ALDOSTERONE DURING INTENSE HEAT-STRESS
PLASMA-RENIN ACTIVITY, ANGIOTENSIN-II, AND ALDOSTERONE DURING INTENSE HEAT-STRESS
复制标题
DOI：
10.1152/jappl.1976.41.3.323
复制
发表时间：
1976-01-01
影响因子：
3.3
通讯作者：
ADLERCREUTZ, H
中科院分区：
文献类型：
--
作者：
KOSUNEN, KJ;PAKARINEN, AJ;ADLERCREUTZ, H
对6名男大学生桑拿浴热应激前后血浆肾素活性（PRA）、血管紧张素Ⅱ（Ang Ⅱ）、醛固酮（ALD）水平、动脉血压和心率进行了测定。桑拿期间和桑拿后PRA、血管紧张素II和醛固酮水平均升高。PRA的最大平均增加（94.9 . ±. 10.4%SE，P < 0.005）和血管紧张素II（196 . ±.热应激结束时（20 min）血浆醛固酮水平（505 ± 0.54.7%SE，P < 0.02）显著高于对照组（P <0.01）。209%SE，P < 0.02）。在热应激期间，心率大致翻了一番，并且有短暂的增加，随后收缩压下降，舒张压下降。热应激可引起肾素-血管紧张素-醛固酮系统3种主要成分的显著变化。
Plasma renin activity (PRA), angiotensin II and aldosterone levels, arterial blood pressure and heart rate of 6 male students were investigated during and after heat stress in a sauna bath. Increased PRA, angiotensin II and aldosterone levels were found both during and after sauna. The greatest mean increases in PRA (94.9 .+-. 10.4% SE, P < 0.005) and angiotensin II (196 .+-. 54.7% SE, P < 0.02) were observed at the end of the heat stress (at 20 min), and that in plasma aldosterone (505 .+-. 209% SE, P < 0.02) 30 min after the sauna. The heart rate roughly doubled during the heat stress and there was a transient increase followed by a decrease in systolic blood pressure and a decrease in diastolic blood pressure. Intense heat stress can cause remarkable changes in the 3 main components of the renin-angiotensin-aldosterone system.