Long-term exposure to indoor air pollution and risk of tuberculosis.

Long-term exposure to indoor air pollution and risk of tuberculosis.
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DOI:
10.1111/ina.12756
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发表时间:
2021-05
期刊:
影响因子:
5.8
通讯作者:
--
中科院分区:
环境科学与生态学2区
文献类型:
--
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室内空气污染(IAP)是公认的多种疾病的危险因素。本文探讨了室内固体燃料暴露在结核分枝杆菌(TB)的风险在印度德里大都市的作用。采用横断面设计,筛选受试者的活动性结核病史和终身暴露于IAP源,如固体燃料燃烧和煤油。研究区结核病患病率为1117/10万。每年,固体燃料暴露的增加与活动性结核病史的可能性增加3%有关。受试者暴露于固体燃料和煤油使用取暖和烹饪显示出显着的关联与结核病。年龄、家庭支出(收入的代理)、肺功能和吸烟也显示出与结核病的显著关联。吸烟者和接触固体燃料的受试者有活动性结核病史的可能性是不吸烟者和未接触受试者的四倍。这些发现呼吁采取减少固体燃料暴露的战略,例如使用清洁炉灶和通风,以减轻结核病的风险,这与联合国“到2030年消除结核病”的目标相一致。
Indoor air pollution (IAP) is a recognized risk factor for various diseases. This paper examines the role of indoor solid fuel exposure in the risk of mycobacterium tuberculosis (TB) in Delhi Metropolitan, India. Using a cross-sectional design, subjects were screened for a history of active TB and lifelong exposure to IAP sources, such as solid fuel burning and kerosene. The TB prevalence rate in the study area was 1117 per 100 000 population. Every year, increase in solid fuel exposure was associated with a three percent higher likelihood of a history of active TB. Subjects exposed to solid fuel and kerosene use for both heating home and cooking showed significant associations with TB. Age, household expenditure (a proxy of income), lung function, and smoking also showed significant associations with TB. Smokers and solid fuel–exposed subjects were four times more likely to have a history of active TB than non-smoker and unexposed subjects. These finding calls strategies to mitigate solid fuel exposure, such as use of clean cookstove and ventilation, to mitigate the risk of TB which aligns with the United Nations’ goal of “End TB by 2030.”
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