Embryologic Association of Tornwaldt's Cyst with Cerebral Artery Abnormalities and Infarction: A Case Report.
Embryologic Association of Tornwaldt's Cyst with Cerebral Artery Abnormalities and Infarction: A Case Report.
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DOI：
10.1155/2012/129503
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发表时间：
2012
影响因子：
0.9
通讯作者：
Zhang J
中科院分区：
文献类型：
--
作者：
Osborn MF;Buchanan BK;Akle N;Badr A;Zhang J
背景和目的。Tornwaldt‘s囊肿是一种罕见的鼻咽部病变，由胚胎脊索的残留物发展而来。案件摘要。我们报告了一位12岁的女性中风患者，患有Tornwaldt‘s囊肿，她的父亲在52岁时也因腹主动脉瘤而中风，这表明这一病例受遗传因素的影响。结论。本文提出Tornwaldt囊肿与脑血管异常之间的病因学联系是发育过程中脊索功能障碍的结果，可能是发育或生物发生过程中脊索来源的分子信号扰动的结果。
Background and Purpose. Tornwaldt's cysts are rare nasopharyngeal lesions that develop from remnants of the embryonic notochord. Summary of Case. We reported a twelve-year-old female stroke patient with Tornwaldt's cysts, whose father also suffered a stroke at age fifty two with the presence of an abdominal aortic aneurysm, suggesting a genetic influence in this case. Conclusions. This paper suggests an etiologic connection between Tornwaldt's cysts and cerebral vasculature abnormalities by way of notochordal dysfunction during development, likely the result of perturbation of notochord-derived molecular cues during development or biogenesis.