Sugar/steroid/sugar conjugates: Sensitivity of lipid binding to sugar structure
Sugar/steroid/sugar conjugates: Sensitivity of lipid binding to sugar structure
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DOI：
10.1021/ol030084r
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发表时间：
2003-10-30
期刊：
影响因子：
5.2
通讯作者：
Menger, FM
中科院分区：
文献类型：
--
作者：
Mbadugha, BNA;Menger, FM
三种类固醇，每个在环A和D上带有糖，已经合成。它们对脂双层的“融化”行为的影响取决于糖是葡萄糖、半乳糖还是甘露糖。包装限制决定了脂质双层如何响应糖。
[GRAPHIC]Three steroids, each bearing a sugar on rings A and D, have been synthesized. Their effect on the "melting" behavior of a lipid bilayer depends on whether the sugar is glucose, galactose, or mannose. Packing constraints dictate how the lipid bilayer responds to the sugars.