Insecticide susceptibility of Aedes aegypti populations from Senegal and Cape Verde Archipelago
Insecticide susceptibility of Aedes aegypti populations from Senegal and Cape Verde Archipelago
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DOI：
10.1186/1756-3305-5-238
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发表时间：
2012-10-22
影响因子：
3.2
通讯作者：
Diallo, Mawlouth
中科院分区：
文献类型：
--
作者：
Dia, Ibrahima;Diagne, Cheikh Tidiane;Diallo, Mawlouth
背景：2009 年 9 月至 10 月期间，佛得角群岛和塞内加尔同时发生了两起登革热 3 (DEN-3) 流行病。埃及伊蚊被确定为这些流行病的传播媒介，因为在这两个国家都从该物种中分离出了几种 DEN-3 病毒株。使用世界卫生组织诊断生物测定试剂盒对两国两种埃及伊蚊野外菌株对拟除虫菊酯、有机氯、有机磷酸酯和氨基甲酸酯的敏感性进行了调查，以监测其对杀虫剂敏感性的现状。结果：两种测试菌株对滴滴涕具有高度抗药性。发现佛得角菌株对除0.1%残杀威外的所有其他测试的杀虫剂均敏感，这需要进一步研究。达喀尔菌株对 1% 杀螟硫磷和 0.75% 氯菊酯敏感，但对溴氰菊酯、高效氯氟氰菊酯和残杀威的敏感性降低。结论：作为基线结果，我们的观察结果强调要谨慎管理用于控制伊蚊的杀虫剂使用。埃及伊蚊。事实上，它们表明 DDT 对于控制 Ae 不再有效。佛得角和达喀尔的埃及伊蚊种群，并进一步建议对两个地点的残杀威敏感性状况以及伊蚊中的溴氰菊酯和高效氯氟氰菊酯敏感性状况进行彻底的随访。达喀尔的埃及伊蚊种群。因此，非常需要定期监测敏感性，并了解观察到的耐药性/敏感性是否是焦点，对于观察到的耐药性，需要使用生化方法，详细比较大地理区域的耐药性水平。
Background: Two concomitant dengue 3 (DEN-3) epidemics occurred in Cape Verde Archipelago and Senegal between September and October 2009. Aedes aegypti was identified as the vector of these epidemics as several DEN-3 virus strains were isolated from this species in both countries. The susceptibility to pyrethroids, organochlorine, organophosphates and carbamate was investigated in two field strains of Aedes aegypti from both countries using WHO diagnostic bioassay kits in order to monitor their the current status of insecticide susceptibility.Findings: The two tested strains were highly resistant to DDT. The Cape Verde strain was found to be susceptible to all others tested insecticides except for propoxur 0.1%, which needs further investigation. The Dakar strain was susceptible to fenitrothion 1% and permethrin 0.75%, but displayed reduced susceptibility to deltamethrin, lambda-cyhalothrin and propoxur.Conclusions: As base-line results, our observations stress a careful management of insecticide use for the control of Ae. aegypti. Indeed, they indicate that DDT is no longer efficient for the control of Ae. aegypti populations in Cape Verde and Dakar and further suggest a thorough follow-up of propoxur susceptibility status in both sites and that of deltamethrin and lambda-cyhalothrin in Ae. aegypti populations in Dakar. Thus, regular monitoring of susceptibility is greatly needed as well as the knowing if this observed resistance/susceptibility is focal or not and for observed resistance, the use of biochemical methods is needed with detailed comparison of resistance levels over a large geographic area.