sox30:: a novel zebrafish sox gene expressed in a restricted manner at the midbrain-hindbrain boundary during neurogenesis
sox30:: a novel zebrafish sox gene expressed in a restricted manner at the midbrain-hindbrain boundary during neurogenesis
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DOI：
10.1007/s004270050264
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发表时间：
1999-06-01
影响因子：
2.4
通讯作者：
Austin, CA
中科院分区：
文献类型：
--
作者：
De Martino, SP;Errington, F;Austin, CA
Sox蛋白家族被认为在多种发育过程中调节基因表达。本研究克隆了斑马鱼sox基因sox30。原位杂交显示sox30在神经系统发育过程中在中脑和后脑之间的边界以限制性的方式表达。这种表达模式与在整个神经系统中表达的大多数其他神经元表达的Sox基因的表达模式形成直接对比。
The Sox family of proteins is thought to act to regulate gene expression in a wide variety of developmental processes. Here we describe the cloning of sox30, a novel sox gene from the zebrafish (Danio rerio). In situ hybridization shows that sox30 is expressed in a restricted manner at the boundary between the midbrain and hindbrain during nervous system development. This expression pattern is in direct contrast to that of most other neuronally expressed Sox genes which are expressed throughout the nervous system.