Neural encoding of actual and imagined touch within human posterior parietal cortex.
Neural encoding of actual and imagined touch within human posterior parietal cortex.
复制标题
人类后顶叶皮层对实际和想象触摸的神经编码。
DOI：
10.7554/elife.61646
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发表时间：
2021-03-01
期刊：
影响因子：
7.7
通讯作者：
Andersen RA
中科院分区：
文献类型：
--
作者：
Chivukula S;Zhang CY;Aflalo T;Jafari M;Pejsa K;Pouratian N;Andersen RA
在人类后顶叶皮层（PPC）中，单个单元编码具有部分混合表示的高维信息，使得小群体神经元能够编码与运动规划，执行，认知和感知相关的许多变量。在这里，我们测试是否PPC神经元人口先前证明编码视觉和运动信息同样从事体感域。我们记录了人类临床试验参与者的PPC内的神经元在实际触摸演示和触觉成像任务。神经元编码实际触摸在短潜伏期与双边感受野，组织身体的一部分，并覆盖所有测试区域。触觉想象任务引起的身体部位的具体反应，共享与实际触摸的神经基板。我们的研究结果是人类PPC中触摸编码及其在触觉图像任务中的认知参与的第一个神经元水平的证据，这可能反映了语义处理，注意力，感官预期或想象的触摸。
In the human posterior parietal cortex (PPC), single units encode high-dimensional information with partially mixed representations that enable small populations of neurons to encode many variables relevant to movement planning, execution, cognition, and perception. Here, we test whether a PPC neuronal population previously demonstrated to encode visual and motor information is similarly engaged in the somatosensory domain. We recorded neurons within the PPC of a human clinical trial participant during actual touch presentation and during a tactile imagery task. Neurons encoded actual touch at short latency with bilateral receptive fields, organized by body part, and covered all tested regions. The tactile imagery task evoked body part-specific responses that shared a neural substrate with actual touch. Our results are the first neuron-level evidence of touch encoding in human PPC and its cognitive engagement during a tactile imagery task, which may reflect semantic processing, attention, sensory anticipation, or imagined touch.