Droplet on demand system utilizing a computer controlled microvalve integrated into a stiff polymeric microfluidic device
Droplet on demand system utilizing a computer controlled microvalve integrated into a stiff polymeric microfluidic device
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DOI：
10.1039/b915155a
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发表时间：
2010-01-01
期刊：
影响因子：
6.1
通讯作者：
Garstecki, Piotr
中科院分区：
文献类型：
--
作者：
Churski, Krzysztof;Michalski, Jacek;Garstecki, Piotr
在刚性聚合物（聚碳酸酯）装置中制造的集成微阀允许形成任意体积的液滴和气泡并且在任意发射时间。体积序列、液滴之间的间隔及其化学成分的形成的预先设计的方案可以实际上和可再现地实现，并由个人计算机控制。微阀的设计使其能够用于由一系列其他材料（包括塑料和玻璃）制成的芯片中，以及用于在正压和负压下操作的装置中，从而为微流体液滴系统的一系列应用提供有用的模块。
An integrated microvalve fabricated in a stiff polymeric (polycarbonate) device allows for formation of droplets and bubbles of arbitrary volumes and at arbitrary times of emission. Predesigned protocols of formation of sequences of volumes, intervals between the droplets and their chemical compositions can be practically and reproducibly realised and controlled from a personal computer. The design of the microvalve enables its utilization in chips made in a range of other materials, including plastics and glass and in devices operated both with positive and negative pressure providing a useful module for a range of applications of microfluidic droplet systems.