Effects of self-assessed chewing ability, tooth loss and serum albumin on mortality in 80-year-old individuals: a 20-year follow-up study
Effects of self-assessed chewing ability, tooth loss and serum albumin on mortality in 80-year-old individuals: a 20-year follow-up study
复制标题
DOI：
10.1186/s12903-020-01113-7
复制
发表时间：
2020-04-21
期刊：
影响因子：
2.9
通讯作者：
Hanada, Nobuhiro
中科院分区：
文献类型：
--
作者：
Nomura, Yoshiaki;Kakuta, Erika;Hanada, Nobuhiro
背景：社区老年人的牙齿状况和死亡率之间的关系已被多项研究所证实。本研究的目的是分析自我评估的咀嚼能力、剩余牙齿数量和血清白蛋白水平对死亡率的贡献以及这三个因素之间的交互作用。方法对岩手县某卫生院服务的8个地区的666名80岁老人(1996年至2017年)进行为期20年的随访研究。健康检查，包括身体健康测量，在会议场所或健身房进行。由内科医生进行医学问诊和采血。口腔检查由牙医检查。剩余牙齿的数量、血清白蛋白水平和自我评估的咀嚼能力被用作死亡率的预测因子。结果608例受试者(男233例，女375例)经20年随访，仅12例存活(1.97%)。对于男性来说，牙齿状况和血清白蛋白水平与死亡率显著相关。通过项目反应理论分析计算的自我评估咀嚼能力的风险比，以及无法咀嚼至少一种根据血清白蛋白和牙齿状况进行调整的食物的风险比在男性中具有统计学意义。当根据血液测试评估的健康状况进行调整时，自我评估的咀嚼能力在男性中具有统计学意义。根据通径分析，自我评估的咀嚼能力和血清白蛋白独立影响男性的死亡率。结论咀嚼功能障碍可能是男性死亡的一个重要危险因素，即使它是自我评估的。保持咀嚼能力可能是预测老年男性寿命的有用指标。
Background The association between dental status and mortality in community-dwelling older adults has been documented by several studies. The aim of this study was to analyze the contribution of self-assessed chewing ability, number of remaining teeth and serum albumin levels to mortality and the interactions between the three factors. Methods A 20-year follow-up study was conducted with 666 subjects aged 80 years (from 1996 to 2017) who resided in the 8 areas served by one health center in Iwate Prefecture. Health check-ups including physical fitness measurements were conducted at a meeting place or gymnasium. Medical interview and blood sampling were conducted by physician. Oral examination was examined by dentist. The number of remaining teeth, serum albumin levels, and self-assessed chewing ability were used as predictors of mortality. Results Among the 608 subjects (233 men and 375 women) included in this study, only 12 subjects (1.97%) survived after 20 years of follow-up. For men, dental status and serum levels of albumin were significantly associated with mortality. The hazard ratios of self-assessed chewing ability calculated by item response theory analysis and the inability to chew at least one food adjusted for serum albumin and tooth conditions were statistically significant in men. When adjusted by health status evaluated by blood tests, self-assessed chewing ability was statistically significant in men. According to path analysis, self-assessed chewing ability and serum albumin independently affected mortality in men. Conclusion Masticatory dysfunction may be an important risk factor for mortality in men, even though it was self-assessed. Retaining chewing ability might be a useful predictor of longevity in older male adults.