Individual Differences in Bait Shyness: Effects of Drug Dose and Measurement Technique
Individual Differences in Bait Shyness: Effects of Drug Dose and Measurement Technique
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诱饵害羞的个体差异：药物剂量和测量技术的影响
DOI：
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发表时间：
1973
期刊：
影响因子：
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通讯作者：
R. Elkins
中科院分区：
文献类型：
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作者：
R. Elkins
通过操纵毒性剂量大小和测量技术，重新检查了大鼠诱饵害羞的特征在于缺乏个体差异的结论。个体差异收购环磷酰胺引起的厌恶糖精味的水记录，即使相对不敏感的单瓶测量程序。然而，单瓶消退相当迅速，且不依赖于剂量。与此相反，敏感的2瓶测量程序显示剂量依赖性的个体差异，在厌恶收购和灭绝的阻力。结果进行了讨论的关系，厌恶疗法治疗酒精中毒。
The conclusion that bait shyness in rats is characterized by a paucity of individual differences was reexamined through manipulation of toxic-dose magnitudes and measurement techniques. Individual differences in acquisition of a cyclophosophamide-induced aversion to saccharin flavored water were recorded even with relatively insensitive single-bottle measurement procedures. However, single-bottle extinction was quite rapid and dose independent. In contrast, sensitive 2-bottle measurement procedures revealed dose-dependent individual differences in both aversion acquisition and resistance to extinction. Results are discussed in relationship to aversion therapy treatment of alcholism.