Treatment of masseteric hypertrophy with botulinum toxin: A report of two cases
Treatment of masseteric hypertrophy with botulinum toxin: A report of two cases
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DOI：
10.4317/medoral.15.e649
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发表时间：
2010-07-01
影响因子：
2.2
通讯作者：
Celebi, Nuekhet
中科院分区：
文献类型：
--
作者：
Bas, Burcu;Ozan, Bora;Celebi, Nuekhet
咬肌肥大是一种罕见的原因不明的情况，这是重要的鉴别诊断头颈部肿块，位于脸颊。据报道，咬肌肥大有几种治疗方法，从简单的药物治疗到更具侵入性的手术复位。A型肉毒杆菌毒素是一种强效的神经毒素，由厌氧生物肉毒梭菌产生，当注射到肌肉时，会干扰神经递质机制，产生选择性麻痹和随后的肌肉萎缩。在咬肌注射A型肉毒杆菌毒素通常被认为是一种侵入性较小的方式，并且一直被提倡用于下面部的美容雕刻。A型肉毒毒素注射被认为是治疗咬肌肥大的一种有效方法。本文报告两例用A型肉毒毒素注射治疗咬肌肥大的病例。术后3个月，患者面部特征有明显变化。
Masseter muscle hypertrophy is a rare condition of unknown cause which is important in the differential diagnosis of head and neck masses, located in the cheek. Several treatment options reported for masseter hypertrophy, which range from simple pharmacotherapy to more invasive surgical reduction. Botulinum toxin type A is a powerful neurotoxin which is produced by the anaerobic organism Clostridium botulinum and when injected into a muscle causes interference with the neurotransmitter mechanism producing selective paralysis and subsequent atrophy of the muscle. Injection of botulinum toxin type A into the masseter muscle is generally considered a less invasive modality and has been advocated for cosmetic sculpting of the lower face. Botulinum toxin type A injection is considered to be a beneficial treatment modality in masseter muscle hypertrophy patients. The aim of this article is to report two cases of masseteric muscle hypertrophy which were treated with botulinum toxin type A injection. Marked changes in facial feature were achieved 3 months after the procedure.