Hearing recovery from deafness caused by bromate intoxication
Hearing recovery from deafness caused by bromate intoxication
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DOI：
10.1017/s0022215118002001
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发表时间：
2018-11-01
影响因子：
1.7
通讯作者：
Katori，Y.
中科院分区：
文献类型：
--
作者：
Suzuki，J.;Takanashi，Y.;Katori，Y.
目的溴酸钠是一种强氧化剂，溴酸盐中毒可导致不可逆转的严重至深度感音神经性听力损失。本文报道了英国文献中首例经正式听力学检查证实听力恢复的溴酸盐致听力损失病例。病例报道，一名72岁女性在自杀未遂中摄入溴酸盐后，主诉听力严重丧失、恶心、腹泻和无尿。入院时，纯音测听和听性脑干反应显示双侧深度耳聋。在诊断为溴酸盐所致急性肾功能衰竭和感音神经性耳聋的情况下，进行连续性血液透析滤过。停止透析时，纯音测听和听性脑干反应显示深度耳聋部分恢复。结论重度感音神经性听力损失是溴酸盐中毒的常见症状。溴酸盐引起的听力损失可能会得到部分治疗，早期应用连续性血液透析滤过可能是治疗这种顽固性疾病的有效方法。
ObjectivesSodium bromate is a strong oxidant, and bromate intoxication can cause irreversible severe-to-profound sensorineural hearing loss. This paper reports the first case in the English literature of bromate-induced hearing loss with hearing recovery measured by formal audiological assessment.Case reportA 72-year-old woman was admitted to hospital with complaints of profound hearing loss, nausea, diarrhoea and anuria after bromate ingestion in a suicide attempt. On admission, pure tone audiometry and auditory brainstem responses showed profound bilateral deafness. Under the diagnosis of bromate-induced acute renal failure and sensorineural hearing loss, continuous haemodiafiltration was performed. When dialysis was discontinued, pure tone audiometry and auditory brainstem responses showed partial threshold recovery from profound deafness.ConclusionSevere-to-profound sensorineural hearing loss is a common symptom of bromate intoxication. Bromate-induced hearing loss may be partially treated, and early application of continuous haemodiafiltration might be useful as a treatment for this intractable condition.