CIRCULATION IN EXERCISING DOGS
CIRCULATION IN EXERCISING DOGS
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DOI：
10.1152/jappl.1964.19.1.29
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发表时间：
1964-01-01
影响因子：
3.3
通讯作者：
PIIPER, J
中科院分区：
文献类型：
--
作者：
CERRETELLI, P;CUTTICA, F;PIIPER, J
本文研究了犬在跑步机上以不同的速度和+10%的坡度跑时心血管系统对肌肉运动的调节。热稀释法测得的心输出量随着氧耗量的增加而增加，当氧耗量为70ml/kg min时，心输出量达到520ml/kg min。在更高的代谢水平下，心输出量保持不变，氧耗量仅通过增加动静脉氧分差而增加，在本研究达到的最高耗氧值90ml/kg min时，计算得到的氧耗量为17vol%。心输出量的增加主要是由于心率的增加，而每搏输出量的平均最大增量仅为30%左右。平均动脉压和中心静脉压随运动增加而升高。在突然开始或停止不同强度的运动后，测量心输出量调整的时间进程。开始和恢复时的“半反应时间”约为20秒；1分钟后，心输出量没有进一步的可测量变化。
The adjustments of the cardiovascular system to muscular exercise were studied in dogs running on a treadmill at different speeds and at the incline of + 10%. The cardiac output, measured by the thermodilution method, increased with increasing O2 consumption, reaching 520 ml/kg min at an O2 consumption of 70 ml/kg min. At still higher metabolic levels the cardiac output remained constant and the O2 consumption increased by an increase of the arteriovenous O2 difference only, which was calculated to attain 17 vol % at the highest O2 consumption value reached in this study, 90 ml/kg min. The increase of the cardiac output was mainly due to increase of the heart rate, whereas the average maximum increment of the stroke volume was about 30% only. The mean arterial and the central venous blood pressures increased with exercise. The time course of the adjustment of the cardiac output was measured after the exercise of varied intensity had been abruptly begun or stopped. Both for start and recovery the "half reaction time" was about 20 sec; after 1 min no further measurable change of the cardiac output was detectable.