Copolymerization of photocrosslinkable anhydride monomers for use as a biodegradable bone cement
Copolymerization of photocrosslinkable anhydride monomers for use as a biodegradable bone cement
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DOI：
10.1163/156856203763572716
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发表时间：
2003-01-01
影响因子：
3.6
通讯作者：
Anseth, KS
中科院分区：
文献类型：
--
作者：
Watkins, AW;Anseth, KS
合成了一种多功能酸酐单体甲基丙烯酸癸二酸酐（MSA），并通过光引发聚合与甲基丙烯酸酐共聚形成高度交联的可降解网络。该材料系统作为一种潜在的可降解骨水泥进行了研究。几个方面进行了研究，包括固化特性，降解速率和机械性能。这些共聚物网络在临床上可接受的时间尺度上达到了高双键转化率（
A multifunctional anhydride monomer, methacrylated sebacic anhydride (MSA), was synthesized and copolymerized with methacrylic anhydride via photoinitiated polymerization to form highly crosslinked, degradable networks. This material system was investigated as a potential degradable bone cement. Several aspects were examined, including curing characteristics, degradation rates and mechanical properties. These copolymer networks reached high double-bond conversions on clinically acceptable time scales (