The emerging field of social and behavioral epigenetic

The emerging field of social and behavioral epigenetic
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社会和行为表观遗传学的新兴领域

DOI:
10.1002/9781118900772.etrds0447
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发表时间:
2018
期刊:
Emerging Trends in the Social and Behavioral Sciences
影响因子:
--
通讯作者:
Mulligan, C
Mulligan, C
中科院分区:
--
文献类型:
--
作者:
Mulligan, C

文献摘要

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社会和行为表观遗传学是通过表观遗传机制影响生物学的社会心理因素的研究。表观遗传修饰影响基因的活性而不改变潜在的DNA序列。DNA甲基化是一种表观遗传修饰,已被广泛研究,并发现与广泛的心理社会压力有关。本文回顾了具有里程碑意义的研究和当前的创新。心理社会压力引起的表观遗传变化的进化背景,以及这种变化的可能遗传性,也提出了。社会和行为科学家在这一新兴领域的参与是必不可少的,以确保心理社会环境的细微差别得到很好的理解和准确的建模。
Social and behavioral epigenetics is the study of psychosocial factors that impact biology through an epigenetic mechanism. Epigenetic modifications influence the activity of genes without altering the underlying DNA sequence. DNA methylation is one type of epigenetic modification that has been widely studied and found to associate with a broad range of psychosocial stressors. This paper reviews the landmark studies and current innovations. An evolutionary context for epigenetic changes induced by psychosocial stress, and the possible heritability of such changes, is also presented. The involvement of social and behavioral scientists in this emerging field is essential to ensure that the nuances of the psychosocial environment are well understood and accurately modeled.