A NEW STEROID GLYCOSIDE TACCAOSIDE FROM TACCA-CHEANCER
A NEW STEROID GLYCOSIDE TACCAOSIDE FROM TACCA-CHEANCER
复制标题
DOI：
10.1007/bf00567287
复制
发表时间：
1980-01-01
期刊：
影响因子：
--
通讯作者：
ABUBAKIROV N K
中科院分区：
文献类型：
--
作者：
NGOK F K;KEL'GINBAEV A N;ABUBAKIROV N K
从Tacca cheancer根的乙醇提取物中分离得到一个新的螺甾烷系列甾体苷--Tacacoside（I）。发现酸水解产物以1：2的比例含有糖苷配基薯蓣皂苷元（II）和糖D-葡萄糖和L-鼠李糖。通过全甲基化物（IV）的甲基化和水解，已经确定两个末端L-鼠李糖残基连接在D-葡萄糖分子的C-2和C-3处，D-葡萄糖分子反过来取代薯蓣皂苷元的C-3处的羟基。糖苷（I）的结构为（25 R）-螺甾-5-烯-3 β-醇3-O-{[0-α-L-吡喃鼠李糖基-（1→2）][0-α-L-吡喃鼠李糖基-（1→3）]-β-D-吡喃葡萄糖苷}。
A new steroid glycoside of the spirostan series — taccaoside (I) — has been isolated from an ethanolic extract of the roots ofTacca cheancer(familyTaccaceae). An acid hydrolysate was found to contain the aglycone diosgenin (II) and the sugars D-glucose and L-rhamnose in a ratio of 1:2. By methylation and hydrolysis of the permethylate (IV) it has been established that the two terminal L-rhamnose residues are attached at C-2 and C-3 of the D-glucose molecule which, in its turn, substitutes the hydroxy group at C-3 of diosgenin. Glycoside (I) has the structure of (25R)-spirost-5-en-3β-ol 3-0-{[0-α-L-rhamnopyranosyl-(1→2)][0-α-L-rhamnopyranosyl-(1→3)]-β-D-glucopyranoside}.