ASSOCIATION OF BLASTOCYSTIS-HOMINIS WITH SIGNS AND SYMPTOMS OF HUMAN-DISEASE
ASSOCIATION OF BLASTOCYSTIS-HOMINIS WITH SIGNS AND SYMPTOMS OF HUMAN-DISEASE
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DOI：
10.1128/jcm.24.4.548-550.1986
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发表时间：
1986-10-01
影响因子：
9.4
通讯作者：
MCKITRICK, JC
中科院分区：
文献类型：
--
作者：
SHEEHAN, DJ;RAUCHER, BG;MCKITRICK, JC
对389例患者的净化粪便进行显微镜下评价，以确定是否存在人芽囊原虫。总共有五个或五个以上的B。人细胞/40 ×43例（11%）患者有B.在这些患者中，23例（6%）存在人型寄生虫。23例患者中，19例出现症状，包括腹部不适（15例患者）、厌食（10例患者）、腹泻（9例患者）和胃肠胀气（9例患者）。其余4名患者无症状。在11例（58%）有症状的患者中，外周血中嗜酸性粒细胞的比例范围为4%至12%。8名患者的绝对嗜酸性粒细胞计数大于250/μ l，5名患者的绝对嗜酸性粒细胞计数大于400/μ l。在其余有症状或无症状患者中未观察到嗜酸性粒细胞增多。这项研究支持了B角色的新概念。人类肠道寄生虫导致人类疾病。
Purged stools from 389 patients were evaluated microscopically for the presence of Blastocystis hominis. A total of five or more B. hominis cells per 40 .times. field were observed in 43 patients (11%), and B. hominis was the only intestinal parasite present in 23 (6%) of these patients. Of the 23 patients, 19 had symptoms which included abdominal discomfort (15 patients), anorexia (10 patients), diarrhea (9 patients), and flatus (9 patients). The remaining four patients were asymptomatic. The proportion of eosinophils in the peripheral blood ranged from 4 to 12% in 11 (58%) of the symptomatic patients. Absolute eosinophil counts were greater than 250/.mu.l in 8 patients and greater than 400/.mu.l in 5 patients. Eosinophilia was not observed in the remaining symptomatic or asymptomatic patients. This study supports the emerging concept of the role of B. hominis as an intestinal parasite causative of human disease.