Retro-mode imaging of fibrovascular membrane in proliferative diabetic retinopathy after intravitreal bevacizumab injection
Retro-mode imaging of fibrovascular membrane in proliferative diabetic retinopathy after intravitreal bevacizumab injection
复制标题
DOI：
10.2147/opth.s22843
复制
发表时间：
2011-01-01
影响因子：
2.2
通讯作者：
Kitaoka, Takashi
中科院分区：
文献类型：
--
作者：
Suzuma, Kiyoshi;Tsuiki, Eiko;Kitaoka, Takashi
F10 是一款新型商用扫描激光共焦检眼镜 (SLO)，可以执行多种功能。我们确定了使用 F10 SLO 逆向模式功能的新型间接观察系统在玻璃体内注射贝伐单抗 (IVB) 前后对增殖性糖尿病视网膜病变 (PDR) 病理进行无创评估的有用性，并将组织学图像与来自两个病例的手术切除的纤维血管膜进行比较。在 PDR 中，即使在 IVB 后并且没有血流，在逆向模式下也可以清楚地看到纤维血管膜中的新生血管。 F10 SLO 可用于评估 PDR 中纤维血管膜中的新生血管，并可用于确定糖尿病视网膜病变的精确视网膜变化。
The F10 is a new commercially available scanning laser confocal ophthalmoscope (SLO) that can perform multiple functions. We determined the usefulness of noninvasive evaluation of proliferative diabetic retinopathy (PDR) pathologies before and after intravitreal injection of bevacizumab (IVB) using the new indirect viewing system of the retro-mode function of the F10 SLO, and compared the images histologically with surgically excised fibrovascular membrane from two cases. In PDR, neovascular vessels in fibrovascular membrane were clearly seen with the retro-mode, even after IVB and without blood flow. The F10 SLO may be useful in evaluating neovascular vessels in fibrovascular membrane in PDR and for determining the precise retinal changes in diabetic retinopathy.