METABOLITES OF 3 MARINE SPONGES OF THE GENUS PLAKORTIS
METABOLITES OF 3 MARINE SPONGES OF THE GENUS PLAKORTIS
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DOI：
10.1021/jo01305a005
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发表时间：
1980-01-01
影响因子：
3.6
通讯作者：
FAULKNER, DJ
中科院分区：
文献类型：
--
作者：
STIERLE, DB;FAULKNER, DJ
P. halicondrioides 的一份样品含有环状过氧化物 3-epiplakortin 和 9,10-二氢-3-epiplakortin。储存在乙醇中的P.halichondrioides的第二个样品给出了α，β-不饱和酯作为主要的次级代谢物。冷冻和冻干的同一海绵的一部分含有酯和内酯以及两种过氧化物，并且具有不同但密切相关的C骨架。样本被鉴定为 Plakortis sp。含有 2 种不稳定的过氧化物和一种相关的芳香烃。所有结构均通过光谱数据的解释和有限的化学降解反应来阐明。讨论了这些结果的化学分类学意义。
One sample of P. halichondrioides contained the cyclic peroxides 3-epiplakortin and 9,10-dihydro-3-epiplakortin. A 2nd sample of P. halichondrioides that was stored in ethanol gave an .alpha.,.beta.-unsaturated ester as the major secondary metabolite. A portion of the same sponge that was frozen and lyophilized contained the ester and the lactone together with the 2 peroxides, and having a different but closely related C skeleton. A sample identified as Plakortis sp. contained 2 unstable peroxides and a related aromatic hydrocarbon. All structures were elucidated by interpretation of spectral data and limited chemical-degradation reactions. The chemotaxonomic implications of these results are discussed.