Depression among Adult HIV/AIDS Patients Attending ART Clinics at Aksum Town, Aksum, Ethiopia: A Cross-Sectional Study.
Depression among Adult HIV/AIDS Patients Attending ART Clinics at Aksum Town, Aksum, Ethiopia: A Cross-Sectional Study.
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DOI：
10.1155/2019/3250431
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发表时间：
2019-01-01
影响因子：
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通讯作者：
Angesom, Teklit
中科院分区：
文献类型：
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作者：
Beyene Gebrezgiabher, Berhe;Huluf Abraha, Teklehaymanot;Angesom, Teklit
背景技术背景：抑郁症始终与人类免疫缺陷病毒感染风险增加和抗逆转录病毒治疗依从性差相关。虽然许多因素已被报道为抑郁症的决定性因素，网站的具体证据是需要确定与抑郁症的成人抗逆转录病毒therapeutic.METHODS：一个机构为基础的横断面研究进行了从2015年3月至5月的411名成人艾滋病毒/艾滋病患者ART门诊随访。使用系统随机抽样技术选择参与者。数据收集使用图表审查和访谈者管理的技术。使用SPSS 20版本进行双变量和多变量logistic回归计算统计检验关联。结果：411例患者平均年龄36.1±9.2岁，总有效率97.6%。抑郁的患病率为14.6%（95%CI，10.90-18.2）。与抑郁症独立相关的因素有不坚持ART、每天吃两餐或更少、ART药物副作用、HIV/AIDS处于WHO II期或以上、独居，AOR（95%CI）为3.3（1.436，7.759），2.8（1.382，5.794），4.7（1.317，16.514），2.8（0.142，0.786）和2.4（1.097，5.429）。虽然抑郁的程度相对较低，在接受抗逆转录病毒治疗的成人HIV/AIDS患者中，这通常被视为一种心理健康问题。应加强咨询和密切随访抗逆转录病毒治疗依从性、药物副作用和营养的计划。保健设施应将独居的艾滋病毒/艾滋病成年患者与政府和非政府社会支助组织联系起来。
BACKGROUND: Depression is consistently associated with increased risk of Human Immunodeficiency Virus infection and poor antiretroviral treatment adherence. Though many factors have been reported as determinant factors of depression, site-specific evidence is needed to identify factors associated with depression among adults on antiretroviral treatment.METHODS: An institution based cross-sectional study was carried out from March to May 2015 among 411 adults HIV/AIDS patients on ART clinic follow-up. Participants were selected using systematic random sampling techniques. Data were collected using chart review and interviewer- administered techniques. Both bivariable and multivariable logistic regressions were used to compute the statistical test associations by SPSS version-20. Variables with p value < 0.05 were considered as statistically significant.RESULTS: Four hundred eleven patients with a mean age ± Standard Deviation of 36.1±9.2 years and with a total response rate of 97.6% were enrolled in the study. The prevalence of depression was 14.6% (95% CI, 10.90-18.2). Factors independently associated with depression were nonadherence to ART, eating two meals per day or less, having side effect of ART medication, being in the WHO Stage II or above of HIV/AIDS, and living alone with AOR (95% CI) of 3.3 (1.436, 7.759), 2.8 (1.382, 5.794), 4.7 (1.317, 16.514), 2.8 (0.142, 0.786), and 2.4 (1.097, 5.429), respectively.CONCLUSION: Though the magnitude of depression was found relatively low, it was commonly observed as a mental health problem among adult patients with HIV/AIDS on ART. Programs on counseling and close follow-up of adherence to ART, drug side effects, and nutrition should be strengthened. Health facilities should link adult patients with HIV/AIDS who live alone to governmental and nongovernmental social supporter organizations.