The application of exposure therapy and D-cycloserine to the treatment of anorexia nervosa: a preliminary trial.
The application of exposure therapy and D-cycloserine to the treatment of anorexia nervosa: a preliminary trial.
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DOI：
10.1097/01.pra.0000281484.89075.a8
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发表时间：
2007-07-01
影响因子：
1.9
通讯作者：
Walsh, B Timothy
中科院分区：
文献类型：
--
作者：
Steinglass, Joanna;Sysko, Robyn;Walsh, B Timothy
OBJECTIVE: Novel approaches to the treatment of anorexia nervosa (AN) are needed. This preliminary study examined the utility and safety of an exposure therapy intervention and D-cycloserine (DCS) in a population of patients with AN.METHOD: Eleven participants completed a series of 6 laboratory meals, including pre- and post-exposure test meals and four exposure sessions. Participants were randomly assigned to receive either DCS or placebo in double-blind fashion before each of the 4 exposure sessions. These results were compared to data from a previously studied group of patients who received treatment as usual.RESULTS: Total caloric intake increased significantly from the baseline meal session to the post-test meal session in the patients who received the exposure therapy intervention. Caloric intake did not increase significantly in the comparison group.CONCLUSION: These data suggest that an exposure therapy intervention specifically focused on meal consumption may be helpful in increasing intake of a test meal.
