Relationship between vitamin use, smoking, and nausea and vomiting of pregnancy
Relationship between vitamin use, smoking, and nausea and vomiting of pregnancy
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DOI：
10.1034/j.1600-0412.2003.00307.x
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发表时间：
2003-10-01
影响因子：
4.3
通讯作者：
Åberg, A
中科院分区：
文献类型：
--
作者：
Källén, B;Lundberg, G;Åberg, A
背景妊娠期恶心和呕吐（NVP）是一种常见的主诉，但NVP的危险因素尚未得到很好的表征。采用问卷调查的方法，对首次到产前检查单位就诊的孕妇进行NVP的调查，并于孕28周左右进行问卷调查。对3675份完整的问卷进行了分析。79%的妇女报告了怀孕期间的恶心和呕吐，其中大约一半是呕吐。18%的NVP妇女尝试了各种疗法（药物、针灸、指压），其中大多数使用药物，最明显的是抗组胺药（特别是美克洛嗪）。住院率为1%。在怀孕的前28周，恶心和呕吐占所有病假的28%。低产妇年龄和产次1+独立增加NVP的风险。怀孕前吸烟和怀孕早期使用维生素与NVP风险降低有关。外出工作的妇女比家庭主妇和失业妇女的NVP率低。怀孕期间的恶心和呕吐是一种常见的投诉，对请假有重大影响。该研究确定了一些与NVP发生相关的因素，并可能提示该疾病的病因。
Background. Nausea and vomiting in pregnancy (NVP) is a common complaint but risk factors for NVP are not well characterized.Methods. Occurrence of NVP was studied by questionnaires given to pregnant women at their first visit to the antenatal care unit and were returned around gestational week 28.Results. Analysis of 3675 completed questionnaires was made. Nausea and vomiting in pregnancy was reported by 79% of the women, approximately half of which had been vomiting. Various therapies (drugs, acupuncture, acupressure) were tried by 18% of the women with NVP, of which the majority used drugs, most notably antihistamines (specifically meclozine). Hospitalization occurred in 1% of all women. Nausea and vomiting in pregnancy caused 28% of all sick-leaves during the first 28 weeks of pregnancy. Low maternal age and parity 1+ independently increased the risk for NVP. Smoking before pregnancy and using vitamins in early pregnancy were associated with a decreased risk for NVP. Women working outside the home had a lower rate of NVP than housewives and women out of work.Conclusions. Nausea and vomiting in pregnancy is a common complaint with a significant impact on leave of absence from work. The study identifies a number of factors that are related to the occurrence of NVP and that may give hints on the etiology of the condition.