Stillbirths in Macaca fascicularis.
Stillbirths in Macaca fascicularis.
复制标题
食蟹猴的死产。
DOI：
10.1111/j.1600-0684.2007.00275.x
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发表时间：
2008
影响因子：
0.7
通讯作者：
Hubbard,GeneB
中科院分区：
文献类型：
--
作者：
Sesbuppha,Wacharaporn;Chantip,Surachai;DickJr,EdwardJ;Schlabritz-Loutsevitch,NataliaE;Guardado-Mendoza,Rodolfo;Butler,StephanieD;Frost,PatriceA;Hubbard,GeneB
背景：在非人灵长类动物中，死产是一个主要问题，它代表着由于各种内源性、不确定或环境因素，母体-胎儿-胎盘单元未能维持正常关系。方法回顾性分析7年来美洲猕猴群落236例死胎及其胎儿的资料。结果7年死产发生率为11.99%（死产236例，活产1967例）。大多数（61.02%,n=144）病因不明。胎儿病因包括创伤（22.46%,n=53）、胎儿肺炎（0.85%,n=2）和先天性异常（0.42%,n=1）。产妇原因包括难产（9.75%,n=23）和子宫破裂（0.42%,n=1）。49个胎盘可用于组织学评估；胎盘炎5例，坏死5例，胎盘早剥2例。大多数死产发生在足月附近。第一次死产通常发生在8 - 12岁的动物前6次怀孕期间。结论多数死产病因不明。胎儿创伤是最常见的原因。
BackgroundStillbirths in non‐human primates are a major problem and represent failure of the maternal–fetal–placental unit to maintain normal relationships because of various endogenous, undetermined or environmental factors.MethodsRecords of 236 stillborns and their dams in aMacaca fasciculariscolony during a 7‐year period were reviewed retrospectively.ResultsThe 7‐year stillbirth incidence was 11.99% (236 stillbirths, 1967 live births). Most (61.02%, n=144) were of undetermined etiology. Fetal causes included trauma (22.46%, n=53), fetal pneumonia (0.85%, n=2) and congenital anomalies (0.42%, n=1). Maternal causes included dystocia (9.75%, n=23) and uterine rupture (0.42%, n=1). Forty‐nine placentas were available for histologic evaluation; there was placentitis in five, necrosis in five and placental abruption in two. Most stillbirths occurred close to term. First stillbirths usually occurred in 8‐ to 12‐year‐old animals during the first six pregnancies.ConclusionsMost stillbirths were of undetermined etiology. Fetal trauma was the most common cause.