COMPARATIVE PHYTOCHEMICAL STUDY OF DITERPENES OF SOME SPECIES OF GENERA EUPHORBIA AND ELAEOPHORBIA (EUPHORBIACEAE)
COMPARATIVE PHYTOCHEMICAL STUDY OF DITERPENES OF SOME SPECIES OF GENERA EUPHORBIA AND ELAEOPHORBIA (EUPHORBIACEAE)
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DOI：
10.1111/j.1095-8339.1977.tb01163.x
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发表时间：
1977-01-01
影响因子：
2.4
通讯作者：
KINGHORN, AD
中科院分区：
文献类型：
--
作者：
EVANS, FJ;KINGHORN, AD
近60种spp。大戟属Euphorbia L.和Elaeophorbia Stapf进行了调查的二萜的tigliane，ingenane和ortho-ester类。二萜类化合物是通过显微技术从乳胶或从世界各地的几个国家收集的新鲜草药材料中分离出来的。二萜的鉴定是通过色谱手段，使用光谱方法作为备份数据。这些化合物不存在，只有9%的物种检查。最常见的二萜是巨大戟醇，其次是12-脱氧佛波醇。巨大戟烷衍生物5-脱氧巨大戟醇总是被检测到作为一个次要的伴侣巨大戟醇从部分Tithymalus的物种。大戟组的物种主要含有巨大戟二萜醇，尽管在一些物种中存在惕各烷和原酸酯二萜。来自三分叶和一品红组的物种不含所讨论类型的二萜，而来自Elaeophorbia属的物种产生巨大戟醇。这些结果提供了额外的化学证据，最近建议的亚属和属地位的[组] Anisophyllum，一品红，Tithymalus和Elaeophorbia。
Nearly 60 spp. from the genera Euphorbia L. and Elaeophorbia Stapf were investigated for diterpenes of the tigliane, ingenane and ortho-ester classes. The diterpenes were isolated as their acetates by a micro-technique from latex or fresh herb material collected from several countries around the world. Authentication of the diterpenes was by chromatographic means using spectroscopic methods as back-up data. These compounds were absent from only 9% of the species examined. The most commonly occurring diterpene was ingenol, followed closely by 12-Deoxy phorbol. The ingenane derivative 5-Deoxy-ingenol was always detected as a minor companion to ingenol from species of the section Tithymalus. Species of the section Euphorbium contained mainly the diterpene ingenol although both tigliane and ortho-ester diterpenes were present in some species. Species from the sections Anisophyllum and Poinsettia did not contain diterpenes of the type in question, while species from the genus Elaeophorbia yielded ingenol. These results provide additional chemical evidence concerning recent suggestions on the subgeneric and generic status of [sections] Anisophyllum, Poinsettia, Tithymalus and Elaeophorbia.