Leiomyosarcoma in urinary bladder after cyclophosphamide therapy for retinoblastoma and review of bladder sarcomas.
Leiomyosarcoma in urinary bladder after cyclophosphamide therapy for retinoblastoma and review of bladder sarcomas.
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DOI：
10.1016/s0090-4295(02)01701-6
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发表时间：
2002-07-01
期刊：
影响因子：
2.1
通讯作者：
Smith, Ernest R Jr
中科院分区：
文献类型：
--
作者：
Parekh, Dipen J;Jung, Charlie;Smith, Ernest R Jr
我们报告一例视网膜母细胞瘤化疗后发生膀胱平滑肌肉瘤的罕见病例，并对已发表的有关膀胱肉瘤的报道进行综述。一位22岁男性，以血尿为主诉，经电脑断层扫描发现膀胱内有肿块。经尿路肿瘤电切术发现有一平滑肌肉瘤。患者接受了根治性膀胱切除术，并建立了回肠管道。最后的病理检查证实为高度恶性的平滑肌肉瘤。在儿科人群中进行类似于组间横纹肌肉瘤研究的前瞻性随机联合试验对于更好地了解和管理这些潜在可治愈的肉瘤是必要的。
We report an unusual case of a leiomyosarcoma of the urinary bladder after chemotherapy for retinoblastoma and the results of a review of the published reports of bladder sarcomas. A 22-year-old man presented with hematuria and was found to have a mass in his urinary bladder on computed tomography. Transurethral resection of the mass revealed a leiomyosarcoma. The patient underwent radical cystectomy and an ileal conduit was created. The final pathologic examination confirmed high-grade leiomyosarcoma. Prospective randomized combination trials similar to the Intergroup Rhabdomyosarcoma Study in the pediatric population are necessary to better understand and manage these potentially curable sarcomas.