Ultrasound biomicroscopy in the subtypes of primary angle closure glaucoma
Ultrasound biomicroscopy in the subtypes of primary angle closure glaucoma
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DOI：
10.1097/01.ijg.0000176934.14229.32
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发表时间：
2005-10-01
影响因子：
2
通讯作者：
Pandey, RM
中科院分区：
文献类型：
--
作者：
Sihota, R;Dada, T;Pandey, RM
目的：利用超声生物显微镜评估原发性闭角型青光眼（PACG）各亚型的眼前节参数。
方法：本研究纳入5组患者，每组包括30例连续患者，分别被诊断为亚急性PACG、急性PACG、慢性PACG、原发性开角型青光眼（POAG）以及健康对照组。所有患者均接受裂隙灯生物显微镜检查、直接检眼镜检查、90D眼底检查、房角镜检查、压平眼压测量、视野检查、A超生物测量以及超声生物显微镜（UBM）检查。记录的眼前节参数包括：小梁 - 虹膜夹角、房角开放距离、小梁 - 睫状体距离以及虹膜厚度等参数。
结果：在超声生物显微镜下，对照组和POAG组的小梁 - 虹膜夹角大于PACG的所有亚型（P < 0.001）。亚急性PACG（P < 0.001）和慢性PACG（P = 0.003）的小梁 - 虹膜夹角大于急性PACG。对照组和POAG组的房角开放距离显著大于急性PACG和慢性PACG（P < 0.001）。POAG组和对照组的小梁 - 睫状体距离大于亚急性PACG、急性PACG和慢性PACG。亚急性PACG（P < 0.001）和慢性PACG（P < 0.001）的小梁 - 睫状体距离大于急性PACG。急性PACG患眼在测试的三个不同位置的虹膜厚度最小。前房角（小梁 - 虹膜夹角）与以下参数呈正相关：小梁 - 睫状体距离、房角开放距离、前房深度以及眼轴长度（r² = 0.57）。
结论：原发性闭角型青光眼患眼的虹膜较薄，小梁 - 虹膜夹角、房角开放距离以及小梁 - 睫状体距离较短。急性原发性闭角型青光眼患眼的房角隐窝最窄。
Purpose: To evaluate the anterior segment parameters in the subtypes of primary angle closure glaucoma (PACG) using ultrasound biomicroscopy.Methods: Five groups, each comprising 30 consecutive patients, diagnosed to have subacute PACG, acute PACG, chronic PACG, primary open angle glaucoma (POAG), and healthy controls were included in the present study. All patients underwent slit-lamp biomicroscopy, direct ophthalmoscopy, 90D fundus examination, gonioscopy, applanation tonometry, visual field testing, A-scan biometry, and ultrasound biomicroscopy (UBM). The anterior segment parameters recorded included: trabecular-iris angle, angle opening distance, trabecular ciliary process distance, and the iris thickness among other parameters.Results: On ultrasound biomicroscopy the trabecular iris angle of control and POAG groups was more than all the subtypes of PACG (P < 0.001). The trabecular iris angle of subacute PACG (P < 0.001) and chronic PACG (P = 0.003) was more than acute PACG. Angle opening distance of controls and POAG group was significantly more than acute PACG and chronic PACG (P < 0.001). The trabecular ciliary process distance of POAG group and controls was more than subacute PACG, acute PACG, and chronic PACG. The trabecular ciliary process distance of subacute PACG (P < 0.001) and chronic PACG (P < 0.001) was more than acute PACG. Eyes with acute PACG had the least iris thickness at the three different positions tested. There was a positive correlation between the anterior chamber angle (trabecular iris angle) and the following parameters: trabecular ciliary process distance, angle opening distance, anterior chamber depth, and the axial length (r(2) = 0.57).Conclusion: Eyes with primary angle closure glaucoma have a thinner iris with a shorter trabecular iris angle, angle opening distance, and trabecular ciliary process distance. The eyes with acute primary angle closure glaucoma have the narrowest angle recess.