Pressure indices of myocardial oxygen consumption during pulsatile ventricular assistance.
Pressure indices of myocardial oxygen consumption during pulsatile ventricular assistance.
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心室搏动辅助期间心肌耗氧量的压力指数。
DOI：
10.1097/00002480-198907000-00085
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发表时间：
1989
期刊：
影响因子：
--
通讯作者：
DePaulis,R
中科院分区：
文献类型：
--
作者：
Marks,JD;Pantalos,GM;Riebman,JB;Everett,SD;Burns,GL;Burton,NA;DePaulis,R
将左心室 (LVP) 和心肌内 (IMP) 压力指数与脉动心室辅助期间左心室心肌耗氧量 (MVO 2) 进行比较，以确定是否可以在心室支持条件下预测 MVO 2。在五次急性麻醉小牛实验中，记录 IMP 和 LVP 以用于控制和六种支持条件。辅助条件有异步和同步，1:1或1:2；每种控制模式仅具有心房摄取或心房和心室结合摄取。 IMP 通过在左心室中前外侧壁植入微型压力传感器来测量。 MVO 2 使用放射性微球血流技术和血气数据测定。计算每种情况下 IMP 和 LVP 的峰值收缩压、最大 dP/dt 和 Pdt 的平均值。研究发现，在脉动支持条件下，左心室功能的压力指标与 MVO 2 密切相关。
Left ventricular (LVP) and intramyocardial (IMP) pressure indices were compared with left ventricular myocardial oxygen consumption (MVO 2) during pulsatile ventricular assistance to determine if MVO 2 can be predicted under conditions of ventricular support. During five acute anesthetized calf experiments, IMP and LVP were recorded for control and six conditions of support. The assisted conditions were asynchronous and synchronous, 1: 1 or 1: 2; each control mode with atrial uptake only or combined atrial and ventricular uptake. IMP was measured by implantation of a miniature pressure transducer in the midanteriolateral wall of the left ventricle. MVO 2 was determined using the radioactive microsphere blood flow technique and blood gas data. Mean values of peak systolic pressure, maximum dP/dt, and Pdt were calculated for IMP and LVP for each condition. Pressure indicators of left ventricular function were found to correlate well with MVO 2 during conditions of pulsatile support.