A 3-year oral health dose-response study of sodium monofluorophosphate dentifrices with and without zinc citrate: anti-caries results.
A 3-year oral health dose-response study of sodium monofluorophosphate dentifrices with and without zinc citrate: anti-caries results.
复制标题
含或不含柠檬酸锌的单氟磷酸钠牙膏的 3 年口腔健康剂量反应研究：防龋齿结果。
DOI：
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发表时间：
1988
影响因子：
2.3
通讯作者：
Charles F. A. Downie
中科院分区：
文献类型：
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作者：
Kenneth W. Stephen;Stephen L. Creanor;Joyce I. Russell;Charles K. Burchell;Eric Huntington;Charles F. A. Downie
在苏格兰拉纳克郡，对 3000 名 12 岁儿童进行了一项为期 3 年的临床试验，目的是调查同时含有单氟磷酸钠和柠檬酸锌的牙膏对口腔健康的影响，前者的氟化物含量分别为 1000、1500 和 2500 ppm F。使用含有柠檬酸锌牙膏的儿童组与使用柠檬酸锌牙膏的儿童组之间没有发现龋齿增加的显着差异。同行使用无锌浆料。然而，在所使用的 SMFP 范围内显示出显着的抗龋齿剂量反应。这种剂量反应对于男孩和女孩以及各种类型的牙齿和牙齿表面来说都很明显。
A 3-yr clinical trial has been conducted on 3000 12-yr-old children in Lanarkshire, Scotland, with the aim of investigating the effects on oral health of toothpastes containing both sodium monofluorophosphate and zinc citrate, the former being present at fluoride levels of 1000, 1500, and 2500 ppm F. No significant difference in caries increments was found between the group of children using toothpastes incorporating zinc citrate and their counterparts using zinc-free pastes. However, a significant anti-caries dose-response was demonstrated over the SMFP range used. This dose-response was evident for boys and girls and also for the various types of teeth and tooth surfaces.