A novel spectroscopic probe for molecular chirality
A novel spectroscopic probe for molecular chirality
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DOI：
10.1002/chir.20238
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发表时间：
2006-02-01
期刊：
影响因子：
2
通讯作者：
Shen, YR
中科院分区：
文献类型：
--
作者：
Ji, N;Shen, YR
综述了近年来和频产生技术作为分子手性光谱探针的研究进展。简要介绍了该技术的基本原理，与圆二色性（CD）相比。指出该技术的灵敏度明显优于CD，并对其原因进行了讨论。联萘酚（BN）和氨基酸被用作两种不同类型的手性分子的代表;在其电子跃迁中测得的手性可以通过两种不同的分子模型来理解，分别是早期开发的CD模型的扩展。由振动跃迁产生的旋光或手性SFG较弱，但借助于电子-振动双共振，获得了BN单层膜的振动光谱。通常，光学活性SFG足够敏感以用于探测手性单层和薄膜的原位手性。(c)2006 Wiley-Liss，Inc.
Recent advances in developing sum frequency generation (SFG) as a novel spectroscopic probe for molecular chirality are reviewed. The basic principle underlying the technique is briefly described, in comparison with circular dichroism (CD). The significantly better sensitivity of the technique than CD is pointed out, and the reason is discussed. Bi-naphthol (BN) and amino acids are used as representatives for two different types of chiral molecules; the measured chirality in their electronic transitions can be understood by two different molecular models, respectively, that are extensions of models developed earlier for CD. Optically active or chiral SFG from vibrational transitions are weaker, but with the help of electronic-vibrational double resonance, the vibrational spectrum of a monolayer of BN has been obtained. Generally, optically active SFG is sufficiently sensitive to be employed to probe in-situ chirality of chiral monolayers and thin films. (c) 2006 Wiley-Liss, Inc.