Intraoperative handheld optical coherence tomography forward-viewing probe: physical performance and preliminary animal imaging.

Intraoperative handheld optical coherence tomography forward-viewing probe: physical performance and preliminary animal imaging.
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DOI:
10.1364/boe.3.001404
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发表时间:
2012-06-01
影响因子:
3.4
通讯作者:
Yang VX
Yang VX
中科院分区:
医学2区
文献类型:
--
作者:
Sun C;Lee KK;Vuong B;Cusimano MD;Brukson A;Mauro A;Munce N;Courtney BK;Standish BA;Yang VX

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开发了原型术中手持式光学相干断层扫描 (OCT) 成像探头,用于在开放手术期间提供皮下组织的微米分辨率横截面图像。这种新型人体工程学探头是基于静电驱动光纤设计的,并以临床认可的卡口形神经外科探头的形状封装到导管探头中。测量探针的光学特性,光斑尺寸约为 20 μm,工作距离为 5 mm,视场为 4 mm。在猪股血管成像上测试了该探头用于结构和多普勒频移成像的可行性。
A prototype intraoperative hand-held optical coherence tomography (OCT) imaging probe was developed to provide micron resolution cross-sectional images of subsurface tissue during open surgery. This new ergonomic probe was designed based on electrostatically driven optical fibers, and packaged into a catheter probe in the form factor of clinically accepted Bayonet shaped neurosurgical probes. Optical properties of the probe were measured to have a ~20 μm spot size, 5 mm working distance and 4 mm field of view. Feasibility of this probe for structural and Doppler shift imaging was tested on porcine femoral blood vessel imaging.