INHIBITION OF BONE-FORMATION DURING SPACE-FLIGHT
INHIBITION OF BONE-FORMATION DURING SPACE-FLIGHT
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DOI：
10.1126/science.150643
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发表时间：
1978-01-01
期刊：
影响因子：
56.9
通讯作者：
BAYLINK, DJ
中科院分区：
文献类型：
--
作者：
MOREY, ER;BAYLINK, DJ
测量了在苏联宇宙782号生物卫星上在轨运行19.5天的大鼠的骨形成和骨吸收参数。最显著的影响是骨形成。在飞行过程中，大鼠形成的骨膜骨明显少于地面上的对照大鼠。在骨膜和骨内膜的飞行动物的逮捕线表明，发生了完全停止骨生长。在飞行后26天内，骨形成的缺陷得到纠正。未观察到骨吸收的显著变化。
Parameters of bone formation and resorption were measured in rats orbited for 19.5 days aboard the Soviet Cosmos 782 biological satellite. The most striking effects were on bone formation. During flight, rats formed significantly less periosteal bone than did control rats on the ground. An arrest line at both the periosteum and the endosteum of flight animals suggests that a complete cessation of bone growth occurred. During a 26 day postflight period, the defect in bone formation was corrected. No significant changes in bone resorption were observed.