Induction of airway collapse with subatmospheric pressure in awake patients with sleep apnea.
Induction of airway collapse with subatmospheric pressure in awake patients with sleep apnea.
复制标题
在患有睡眠呼吸暂停的清醒患者中用负压诱导气道塌陷。
DOI：
10.1152/jappl.1984.57.1.140
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发表时间：
1984
期刊：
影响因子：
--
通讯作者：
Cooper,K
中科院分区：
文献类型：
--
作者：
Suratt,PM;Wilhoit,SC;Cooper,K
为了确定阻塞性睡眠呼吸暂停（OSA）清醒患者的咽部气道是否异常，我们测量了清醒受试者（12例OSA患者和12例对照组）咽部气道抵抗施加于鼻的负压塌陷的能力。通过一个紧密贴合的面罩对仰卧位的受试者施加亚大气压。我们测量了面罩处的气流以及面罩、咽部和食管压力。10例患者在施加17 - 40 cmH 2 O的负压时发生气道阻塞。阻塞性睡眠呼吸暂停最轻的2例患者未发生阻塞。10例对照组未发生阻塞; 1例肥胖对照组受试者在使用-52 cmH 2 O时发生部分气道阻塞，另1例使用-41 cmH 2 O时发生部分气道阻塞。我们的结论是，严重阻塞性睡眠呼吸暂停患者在清醒时气道异常，应用负压可能是检测阻塞性睡眠呼吸暂停的一种有用的筛查方法。
To determine whether the pharyngeal airway is abnormal in awake patients with obstructive sleep apnea (OSA), we measured the ability of the pharyngeal airway to resist collapse from subatmospheric pressure applied to the nose in awake subjects, 12 with OSA and 12 controls. Subatmospheric pressure was applied to subjects placed in the supine position through a tightly fitting face mask. We measured airflow at the mask as well as mask, pharyngeal, and esophageal pressures. Ten patients developed airway obstruction when subatmospheric pressures between 17 and 40 cmH2O were applied. Obstruction did not occur in two patients with the least OSA. Obstruction did not occur in 10 controls; one obese control subject developed partial airway obstruction when -52 cmH2O was applied as did another with -41 cmH2O. We conclude that patients with significant OSA have an abnormal airway while they are awake andthat application of subatmospheric pressure may be a useful screening test to detect OSA.