Evolution of a Foundational Model of Physiology: Symbolic Representation for Functional Bioinformatics
Evolution of a Foundational Model of Physiology: Symbolic Representation for Functional Bioinformatics
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生理学基础模型的演变：功能生物信息学的符号表示
DOI：
10.3233/978-1-60750-949-3-336
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发表时间：
2004
影响因子：
--
通讯作者：
C. Rosse
中科院分区：
文献类型：
--
作者：
D. L. Cook;J. Mejino;C. Rosse
我们描述了生理学基础模型（FMP）作为“功能生物信息学”的参考本体的需要。FMP旨在通过集成描述性、定性和定量功能知识来支持符号查找、逻辑推理和数学分析。FMP将作为最初与人类生理学有关的生物功能的象征性表示，并最终扩展到其他物种。我们描述了不断发展的FMP架构，这是基于本体论原则的BioD生物描述语言和解剖学的基础模型（FMA）。
We describe the need for a Foundational Model of Physiology (FMP) as a reference ontology for "functional bioinformatics". The FMP is intended to support symbolic lookup, logical inference and mathematical analysis by integrating descriptive, qualitative and quantitative functional knowledge. The FMP will serve as a symbolic representation of biological functions initially pertaining to human physiology and ultimately extensible to other species. We describe the evolving architecture of the FMP, which is based on the ontological principles of the BioD biological description language and the Foundational Model of Anatomy (FMA).