Predicting symptoms of anxiety and depression in patients living with advanced cancer: the differential roles of hope and optimism

Predicting symptoms of anxiety and depression in patients living with advanced cancer: the differential roles of hope and optimism
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DOI:
10.1007/s00520-018-4215-0
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发表时间:
2018-10-01
影响因子:
3.1
通讯作者:
Rand, Kevin L.
Rand, Kevin L.
中科院分区:
医学2区
文献类型:
--
作者:
Fischer, Ian C.;Cripe, Larry D.;Rand, Kevin L.

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研究目的:晚期癌症患者的心理困扰与功能障碍和生活质量下降有关,并可能对治疗决策产生不利影响。目前对与这种痛苦相关的因素的研究是有限的,使有针对性的干预措施,以减少它次优。我们研究了两个目标相关的期望和两个最常见的症状,心理困扰的晚期癌症患者的生活:焦虑和抑郁symptoms.Methods患者与晚期胃肠道癌,结直肠癌,肺癌,或黑色素瘤(N = 84)完成的措施,焦虑,抑郁症状,乐观,希望和预测12个月的生存。肿瘤学家预测患者12个月的生存率和患者的表现status.Results希望,但不是乐观,与不太严重的抑郁症状(β = -0.42)。相反,乐观,而不是希望,与不太严重的焦虑症状(β = -0.36)。结论希望和乐观似乎与不同方面的心理困扰晚期癌症患者的生活。这可能是由于对晚期癌症患者生活的不确定性和痛苦的不同评价。以希望或乐观为重点的干预措施可以量身定制,以帮助缓解这些患者心理困扰的特定方面。
Purpose Psychological distress is related to poorer functioning and reduced quality of life in patients with advanced cancer and may have untoward influences on treatment decisions. Current research on factors associated with this distress is limited, making targeted interventions to reduce it suboptimal. We examined the relationships between two goal-related expectancies and two of the most common symptoms of psychological distress in patients living with advanced cancer: anxiety and depressive symptoms.Methods Patients with advanced gastrointestinal cancer, colorectal cancer, lung cancer, or melanoma (N = 84) completed measures of anxiety, depressive symptoms, optimism, hope, and prediction for 12-month survival. Oncologists provided prediction for patient 12-month survival and patient performance status.Results Hope, but not optimism, was associated with less severe depressive symptoms (beta = -0.42). Conversely, optimism, but not hope, was associated with less severe anxiety symptoms (beta = -0.36).Conclusions Hope and optimism appear to be associated with different aspects of psychological distress in patients living with advanced cancer. This may be explained by different appraisals of the uncertainty and distress that are associated with living with advanced-stage cancer. Hope- or optimism-focused interventions can be tailored to help alleviate specific aspects of psychological distress among these patients.