Blood pressure and its relationship to plasma lipids and lipoproteins in children: cross-sectional data from the Fels longitudinal study.

Blood pressure and its relationship to plasma lipids and lipoproteins in children: cross-sectional data from the Fels longitudinal study.
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儿童血压及其与血脂和脂蛋白的关系:来自 Fels 纵向研究的横断面数据。

DOI:
10.1016/0091-7435(81)90046-3
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发表时间:
1981
影响因子:
5.1
通讯作者:
Glueck,CJ
Glueck,CJ
中科院分区:
医学2区
文献类型:
--
作者:
Siervogel,RM;Roche,AF;Morris,JG;Glueck,CJ

文献摘要

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Interrelationships of blood pressure and plasma lipid-lipoproteins were examined in cross-sectional data from 62 boys and 57 girls, aged 9 to 18 years. These white children, unselected on the basis of blood pressure or lipid-lipoproteins, are of middle socioeconomic class, live in southwestern Ohio, and are participants in the Fels Longitudinal Study. After covariance adjusting for age and measures of body size and ponderosity, girls in the lowest C-HDL quartile had higher mean systolic blood pressure than those in the top quartile (P= 0.003). Girls in the highest blood pressure quartile had high-density lipoprotein cholesterol (C-HDL) levels lower than those in the lowest blood pressure quartile although the difference was not statistically significant (P= 0.13). There was a significant negative partial correlation (r= −0.31;P= 0.02) in girls between systolic blood pressure and C-HDL levels adjusted for age, fatness, and body size. There were no other consistent, significant relationships between lipid-lipoproteins and blood pressures observed. Associations between lipid-lipoproteins and blood pressure may have important health consequences, since both blood pressure and lipoprotein elevations contribute, synergistically, to coronary heart disease risk, and since both generally maintain their rank order over time from childhood.