Application of quantitative systems pharmacology to guide the optimal dosing of COVID-19 vaccines.
Application of quantitative systems pharmacology to guide the optimal dosing of COVID-19 vaccines.
复制标题
DOI：
10.1002/psp4.12700
复制
发表时间：
2021-10
期刊：
影响因子：
--
通讯作者：
Kierzek AM
中科院分区：
文献类型：
--
作者：
Giorgi M;Desikan R;van der Graaf PH;Kierzek AM
Please try later.
Optimal use and distribution of coronavirus disease 2019 (COVID‐19) vaccines involves adjustments of dosing. Due to the rapidly evolving pandemic, such adjustments often need to be introduced before full efficacy data are available. As demonstrated in other areas of drug development, quantitative systems pharmacology (QSP) is well placed to guide such extrapolation in a rational and timely manner. Here, we propose for the first time how QSP can be applied in the context of COVID‐19 vaccine development.
登录
查看更多内容
DOI：
10.1016/s0140-6736(20)32661-1
发表时间：
2021-01-09
期刊：
Lancet (London, England)
影响因子：
--
作者：
Voysey M;Clemens SAC;Madhi SA;Weckx LY;Folegatti PM;Aley PK;Angus B;Baillie VL;Barnabas SL;Bhorat QE;Bibi S;Briner C;Cicconi P;Collins AM;Colin-Jones R;Cutland CL;Darton TC;Dheda K;Duncan CJA;Emary KRW;Ewer KJ;Fairlie L;Faust SN;Feng S;Ferreira DM;Finn A;Goodman AL;Green CM;Green CA;Heath PT;Hill C;Hill H;Hirsch I;Hodgson SHC;Izu A;Jackson S;Jenkin D;Joe CCD;Kerridge S;Koen A;Kwatra G;Lazarus R;Lawrie AM;Lelliott A;Libri V;Lillie PJ;Mallory R;Mendes AVA;Milan EP;Minassian AM;McGregor A;Morrison H;Mujadidi YF;Nana A;O'Reilly PJ;Padayachee SD;Pittella A;Plested E;Pollock KM;Ramasamy MN;Rhead S;Schwarzbold AV;Singh N;Smith A;Song R;Snape MD;Sprinz E;Sutherland RK;Tarrant R;Thomson EC;Török ME;Toshner M;Turner DPJ;Vekemans J;Villafana TL;Watson MEE;Williams CJ;Douglas AD;Hill AVS;Lambe T;Gilbert SC;Pollard AJ;Oxford COVID Vaccine Trial Group
通讯作者：
Oxford COVID Vaccine Trial Group
DOI：
10.1002/psp4.12063
发表时间：
2016-03
期刊：
CPT: pharmacometrics & systems pharmacology
影响因子：
--
作者：
Allen RJ;Rieger TR;Musante CJ
通讯作者：
Musante CJ
DOI：
10.1136/bmj.n18
发表时间：
2021-01-06
期刊：
BMJ (Clinical research ed.)
影响因子：
--
作者：
Iacobucci, Gareth;Mahase, Elisabeth
通讯作者：
Mahase, Elisabeth
DOI：
10.1056/nejmoa2035389
发表时间：
2021-02-04
期刊：
The New England journal of medicine
影响因子：
--
作者：
Baden LR;El Sahly HM;Essink B;Kotloff K;Frey S;Novak R;Diemert D;Spector SA;Rouphael N;Creech CB;McGettigan J;Khetan S;Segall N;Solis J;Brosz A;Fierro C;Schwartz H;Neuzil K;Corey L;Gilbert P;Janes H;Follmann D;Marovich M;Mascola J;Polakowski L;Ledgerwood J;Graham BS;Bennett H;Pajon R;Knightly C;Leav B;Deng W;Zhou H;Han S;Ivarsson M;Miller J;Zaks T;COVE Study Group
通讯作者：
COVE Study Group
影响因子：
6.7
作者：
Chelliah V;Lazarou G;Bhatnagar S;Gibbs JP;Nijsen M;Ray A;Stoll B;Thompson RA;Gulati A;Soukharev S;Yamada A;Weddell J;Sayama H;Oishi M;Wittemer-Rump S;Patel C;Niederalt C;Burghaus R;Scheerans C;Lippert J;Kabilan S;Kareva I;Belousova N;Rolfe A;Zutshi A;Chenel M;Venezia F;Fouliard S;Oberwittler H;Scholer-Dahirel A;Lelievre H;Bottino D;Collins SC;Nguyen HQ;Wang H;Yoneyama T;Zhu AZX;van der Graaf PH;Kierzek AM
通讯作者：
Kierzek AM