Dietary aflatoxin exposure and impaired growth in young children from Benin and Togo: cross sectional study
Dietary aflatoxin exposure and impaired growth in young children from Benin and Togo: cross sectional study
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DOI：
10.1136/bmj.325.7354.20
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发表时间：
2002-07-06
影响因子：
--
通讯作者：
Wild, CP
中科院分区：
文献类型：
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作者：
Gong, YY;Cardwell, K;Wild, CP
方法和结果我们研究了480名儿童（9个月至5岁），来自16个村庄，在四个地理区域（每个区域4个）：苏丹萨凡纳，几内亚北部萨凡纳草原，几内亚南部萨凡纳草原，沿海萨凡纳。贝宁和多哥的卫生部给予了伦理上的批准，父母给予了知情同意。根据世界卫生组织参考人群的中位数，我们确定了年龄别体重、年龄别身高和身高别体重的z评分。z评分≥ 2被归类为营养不良，≥ 3代表严重营养不良。我们还确定了断奶状态和母亲和家庭的社会经济地位。我们通过测量血液中与白蛋白结合的黄曲霉毒素来评估过去两到三个月的黄曲霉毒素暴露。3
Methods and resultsWe studied 480 children (aged 9 months to 5 years) from 16 villages in four geographic zones (four in each zone): Sudan savannah, north Guinea savannah, south Guinea savannah, and coastal savannah. The Ministries for Health in Benin and Togo gave ethical approval, and parents gave informed consent. We determined weight for age, height for age, and weight for height z scores, according to the median value of a World Health Organization reference population. A z score 2 is classified as malnutrition, and 3 represents severe malnutrition. We also determined weaning status and the socioeconomic status of the mother and family. We assessed aflatoxin exposure over the previous two to three months by measuring aflatoxin bound to albumin in blood. 3